Different genetic structure surrounding the mcr-9 gene. The wbuC, qseC, qseB, and ATPase-encoding genes located downstream of mcr-9 are represented, as well as the different insertion sequences (IS) bracketing that DNA fragment, namely, IS903B, IS1R, IS26-like, and IS15DII. Arrows indicate the sense of transcription of those different genes. (A) Structure surrounding the mcr-9 gene in E. coli isolate 68A (present study) and those identified in silico in Leclercia species (GenBank accession no. CP031102.1), Enterobacter hormaechei (CP031575.1), Salmonella enterica (CP029037.1 and CP006057.1), and Enterobacter kobei (CP032893.1). (B) Structure surrounding the mcr-9 gene identified in silico in Leclercia adecarboxylata (MH909331.1) and Salmonella enterica (CP026661.1). (C) Structure surrounding the mcr-9 gene identified in silico in Enterobacter cloacae (CP020529.1), Salmonella enterica (MK191844.1), Cronobacter sakazakii (CP028975.1), and Enterobacter hormaechei (CP031575.1).