FIG 4.

Analysis of simulated trial data for DHA-PPQ showing the impact of changing follow-up period with follow-up lengths of 28 days, 42 days (as in Fig. 2), and 63 days. Estimated failure rates are shown for the different molecular correction algorithms (Table 1) as a function of FOI and calculated using survival analysis. The multiplicity of infection (MOI) is drawn from data from Tanzania—a relatively high-transmission area.