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Plasma pharmacokinetics of ceftolozane on day 6 after intravenous administration of ceftolozane-tazobactam at 40 (26.3 mg/kg ceftolozane), 80 (53.3 mg/kg ceftolozane), and 160 (106.6 mg/kg ceftolozane) mg/kg every 8 h to healthy New Zealand White rabbits. All values are presented as means from samples of four animals each ± SEM.
