FIG 3.
Influence of DIBI on CST and TGC killing and recovery growth for A. baumannii LAC-4 and ATCC 17978. Cultures of LAC-4 (A and C) or ATCC 17978 (B and D) were inoculated at a final concentration of approximately 5 × 106 CFU/ml in RPMI or in RPMI containing CST (A and B) or TGC (C and D) alone or with DIBI either alone or combined with the antibiotics. Cultures were grown at 35°C with bacterial counts (CFU/ml) being determined at intervals over 24 h. Symbols: control (open circles), DIBI added (open triangles) at 20 μg/ml, antibiotic added (solid circles, CST at 0.5 μg/ml [A] or 0.25 μg/ml [B] or TGC at 0.5 μg/ml [C] or 0.5 μg/ml [D]), or DIBI + antibiotic (solid triangles). Data points are reported as means ± SEM. *, P < 0.05 for DIBI plus antibiotic combinations versus DIBI and antibiotic treatments alone.