Table 4:

Change (Δ) in MRI variables for the injured knee between ACL-R subjects with increase vs. decrease in KAM impulse of the injured knee.

		BL to 6M			6M to 12M
		Decrease ( n= 14)	Increase (n=23)	Padj**	Decrease ( n= 19)	Increase (n=18)	Padj**
Δ T1ρ	Global Femur	1.3 (2.7)	3.8 (2.3)	0.037*	0.1 (2.5)	−0.3 (2.1)	0.674
	cMFa	2.1 (3.6)	4.1 (5.0)	0.446	0.5 (5.1)	−1.8 (2.8)	0.291
	cMFc	0.3 (5.1)	5.6 (4.1)	0.032*	1.6 (4.2)	−1.5 (4.8)	0.170
	cMFp	0.5 (4.0)	3.7 (2.6)	0.037*	0.2 (3.1)	0.4 (3.8)	0.883
	Global Femur	0.3 (3.2)	0.5 (3.9)	0.883	1.9 (1.7)	0.6 (3.4)	0.394
	aMT	0.0 (3.0)	1.3 (3.6)	0.499	1.1 (4.1)	−0.1 (4.1)	0.618
	cMT	0.0 (3.1)	0.7 (4.6)	0.674	1.8 (2.3)	1.1 (4.5)	0.674
	pMT	0.7 (4.7)	0.0 (4.5)	0.802	2.1 (2.2)	0.8 (3.4)	0.407
Δ T2	Global Tibia	0.8 (2.7)	3.0 (1.7)	0.037*	0.8 (2.1)	−0.7 (2.2)	0.152
	cMFa	2.0 (2.7)	3.3 (4.2)	0.568	0.5 (3.2)	−1.4 (2.6)	0.170
	cMFc	−0.1 (3.2)	4.1 (3.2)	0.032*	1.8 (2.6)	−1.0 (4.0)	0.082
	cMFp	0.1 (3.8)	3.2 (2.1)	0.037*	0.5 (2.8)	−0.2 (3.6)	0.764
	Global Tibia	0.6 (2.8)	0.9 (2.4)	0.843	1.2 (2.6)	0.2 (2.7)	0.499
	aMT	1.2 (3.2)	1.0 (3.1)	0.883	0.4 (2.4)	−0.3 (3.4)	0.718
	cMT	0.5 (3.3)	1.5 (3.3)	0.568	0.8 (3.1)	0.6 (3.7)	0.883
	pMT	0.6 (3.4)	0.2 (2.6)	0.830	1.9 (3.2)	0.3 (2.7)	0.291

^*indicates significant p value.

^**P values are from analyses adjusted using Benjamini-Hochberg procedure (q-value).

MRI = magnetic resonance imaging, ACL-R= anterior cruciate ligament, BL = baseline, 6M = 6 month, 12M = 12 month, MF = medial femur, cMFa = anterior portion of central medial femur, cMFc = central portion of central medial femur, cMPp = posterior portion of central medial femur, MT = medial tibia, aMT = anterior medial tibia, cMT = central medial tibia, pMT = posterior medial tibia