Table 3.

EI for the selected EI outcomes

EI outcome, kPa	Malignanta	Benigna	P valueb	ROCc
Median (range), IQR	(n = 77)	(n = 324)		AUC (95% CI)
SWE-ROImean	27 (3–100) 16–41	28 (4–182) 19–37	0.79	0.51 (0.42–0.59)
SWE-ROImax	40 (11–148) 24–62	39 (6–242) 28–50	0.50	0.53 (0.44–0.61)
SWE-ROInn ratio	2.4 (1.0–15.1) 2.0–3.6	2.4 (1.1–27.6) 1.9–3.1	0.13	0.55 (0.48–0.62)
SWE-Stiffmean	33 (4–116) 19–48	32 (4–192) 23–42	0.96	0.52 (0.44–0.60)
SWE-Stiffmax	39 (11–148) 24–58	38 (6–242) 27–49	0.52	0.52 (0.44–0.61)
SWE-Centermeand	17 (4–51) 12–25	16 (4–88) 12–22	0.61	0.52 (0.44–0.61)
SWE-CenterSDd	8.1 (1.5–31.6)	7.1 (1.3–56.5)	0.16	0.56 (0.48–0.64)
	5.1–11.9	5.0–9.6

^aExcluding thyroid micro-carcinoma (n = 9) and nodules with missing EI values (n = 3). ^bTest of difference between median EI between benign and malignant nodules. ^cReceiver-operating characteristic (ROC) analysis area under the curve (AUC) for the prediction of malignancy. An AUC of 0.5 reflects that the optimal cut-off value yields an even chance of a test being true or false positive, while a value of 1.0 reflects that the cut-off value yields 100% sensitivity and specificity. ^d49 nodules did not provide data for the 10 mm center Q-box.

EI, elasticity index; IQR, interquartile range; kPa, kilo Pascal.