. 2019 Jul 24;8(8):1195–1205. doi: 10.1530/EC-19-0324
This work is licensed under a Table 4.
SWE-ROImean tested on cut-off points proposed in previous studies.
| Cut-off pointa | Nodules in previous study | Test of present data on cut-off points proposed in previous studies | ||||
|---|---|---|---|---|---|---|
| n (malignant, %) | Estimates, % (95% CI) | |||||
| Sensitivity | Specificity | PPV | NPV | Accuracy | ||
| 30 kPa (26) | 169 (30) | 46 (34–57) | 58 (53–64) | 21 (15–27) | 82 (77–87) | 56 (51–61) |
| 31 kPa (15) | 313 (62) | 46 (34–57) | 61 (56–66) | 22 (15–28) | 83 (78–87) | 58 (53–63) |
| 34 kPab (24) | 137 (66) | 38 (27–48) | 69 (64–74) | 22 (15–30) | 82 (78–87) | 63 (58–68) |
| 39 kPa (13) | 331 (31) | 26 (16–36) | 80 (75–84) | 23 (14–32) | 82 (78–86) | 69 (65–74) |
| 42 kPa (23) | 62 (27) | 23 (14–33) | 86 (82–90) | 27 (17–38) | 83 (80–87) | 75 (70–79) |
| 49 kPac (22) | 393 (6) | 17 (9–25) | 93 (90–96) | 36 (20–52) | 83 (79–86) | 78 (74–82) |
| 62 kPa (21) | 99 (21) | 9 (3–16) | 97 (95–99) | 41 (18–65) | 82 (78–86) | 80 (76–84) |
| 85 kPa (14) | 476 (80) | 3 (−1 to 6) | 99 (98–100) | 33 (−4 to 71) | 81 (77–85) | 80 (76–84) |
| Rago 2-3 (29) | 195 (20) | 33 (23–43) | 75 (70–80) | 24 (16–32) | 82 (78–87) | 67 (62–71) |
aCut-off points proposed in previous studies were selected for EI outcomes most similar to the definition of SWE-ROImean. bOnly nodules <10 mm. cThe cut-off point with the highest sum of sensitivity and specificity was selected.
kPa, kilo pascals; NPV, negative predictive value; PPV, positive predictive value.