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. 2019 Aug 26;7:223. doi: 10.1186/s40425-019-0693-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Targeting sMIC increases co-stimulatory molecules on CD8 T cells in tumor draining LN and tumor infiltrates. a and b, Representative histograms (a) and summary data (b) demonstrating NKG2D expression on CD8 T cells. c and d, Representative histogram overlay (c) and summary data of mean fluorescence intensity (MFI) (d) demonstrating CD28 expression on CD8 T cells. Grey profiles in (c) are CD28 expression in CD8 T cells from cIgG treated animals. Black profiles in (c) are CD28 expression in CD8 T cells from animals receiving respective therapy