Fig. 4.
Recanalization reduced infarct volume and improved neurological outcomes after MCAO. TTC and Nissl staining were only used to calculate infarct volume. (A) Representative images of TTC stained brain slices; (B) Representative images of Nissl stained brain slices. (C) Quantified infarct volume, (D) Modified Garcia score, (E) Beam walking score, (F) Swimming distance, and (G) Escape latency, & p < 0.05, vs sham, * p < 0.05, vs pMCAO, n = 9 per group, Two-way ANOVA-Sidak; (H) Heatmap image; (I) Target quadrant time, & p < 0.05, vs sham, * p < 0.05, vs pMCAO, n = 9 per group, One-way ANOVA-Tukey. pMCAO, permanent middle cerebral artery occlusion; rMCAO, recanalization at 3 d after MCAO; d, day.