Skip to main content
. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Exp Neurol. 2019 Jul 8;320:113007. doi: 10.1016/j.expneurol.2019.113007

Fig. 7.

Fig. 7.

Effects of FGF21 on neuronal apoptosis via FGFR1/PI3K/Caspase-3 signaling pathway at 1 d after recanalization. (A) Representative Western blots images; (B–H) Quantitative analyses of FGF21, p-FGFR1, FGFR1, PI3K, CC3, Bcl-2, and Bax, & p < 0.05, vs sham, # p < 0.05, vs pMCAO, * p < 0.05, vs rMCAO, @ p < 0.05, vs Scr siRNA, n = 6 per group, One-way ANOVA-Tukey. pMCAO, permanent middle cerebral artery occlusion; rMCAO, recanalization at 3 d after MCAO; Scr siRNA, scrambled siRNA; FGF21, fibroblast growth factor 21; FGFR1, fibroblast growth factor receptor 1; p-FGFR1, phosphorylated FGFR1; PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase; CC3, cleaved Caspase-3; Bcl-2, B-cell lymphoma 2; Bax, Bcl-2-associated X protein.