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. Author manuscript; available in PMC: 2019 Aug 26.
Published in final edited form as: Nature. 2019 Jan 23;566(7742):79–84. doi: 10.1038/s41586-019-0881-4

Extended Data Figure 6. Interface comparison between apo and active mGlu5.

Extended Data Figure 6

Comparison of intersubunit interfaces in apo, and active mGlu5 are. Contact regions (purple) show residues within 4 A of the opposite subunit. Notably, apo mGlu5 lacks any interactions beyond the VFT.