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. 2019 Jul 3;294(34):12743–12753. doi: 10.1074/jbc.RA119.009644

Figure 4.

Figure 4.

Liver-specific overexpression of nuclear SREBP-1a increases hepatic Hamp gene expression under normal chow. A, body weight, and B, relative liver weight of WT and SREBP-1a Tg mice. C, immunoblots of the indicated proteins and D, qRT-PCR analyses of the indicated genes in livers of WT and Tg mice at the age of 3 weeks, or 3 months (E–G). E, correlation analyses between nuclear SREBP-1 protein levels detected by immunoblotting and Hamp mRNA levels measured by qRT-PCR in livers of Tg mice. *, p < 0.05; **, p < 0.01; and ***, p < 0.001 versus WT (n = 7–13).