Term	Definition
Atrophie blanche	Small smooth ivory‐white areas on the skin with hyperpigmented borders and telangiectasias.
Ankyloses	Stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint.
CEAP	Comprehensive classification system developed to allow uniform diagnosis and comparison of patient populations with chronic venous disorders; created by an international ad hoc committee of the American Venous Forum in 1994. CEAP stands for clinical manifestations (C), aetiological factors (E), anatomical distribution (A) and pathophysiological findings (P).
Chronic venous insufficiency	Medical condition in which the veins cannot pump enough blood back to the heart.
Compression therapy	Application of an elastic garment around the leg.
Diapedesis	Passage of blood cells through unruptured walls of a vein or artery into the tissues.
Erysipelas	Acute infection, typically with a skin rash, usually on any of the legs and toes, face, arms or fingers.
Erythema	Superficial reddening of the skin.
Fibrosis	The thickening and scarring of connective tissue.
Hyperpigmentation	Increased pigmentation of an area of the skin.
Lipodermatosclerosis	Inflammation caused by fibrosis of subcutaneous fat.
Lymphoedema	Collection of fluid that causes swelling (oedema) in the arms and legs.
Oedema	Excess of watery fluid collecting in the tissue of the body, swelling caused when fluid leaks out of the body's capillaries.
Placebo	Substance or treatment with no active therapeutic effect.
Salso‐bromojodinated	Type of thermal water
Superficial thrombosis	Inflammatory thrombotic disorder in which a thrombus develops in a vein located near the surface of the skin.
Thrombosis	Local coagulation or clotting of the blood in a part of the circulatory system.
Ultrasound duplex	Non‐invasive evaluation of blood flow through your arteries and veins.
Varicose veins	Gnarled, enlarged veins
Vascular	Relating to blood vessels
Venoactive drugs	Heterogeneous group of medicinal products, which have effects on symptoms related to chronic venous disease.
Venous	Relating to a vein
Venous eczema	Long‐term skin condition that affects the lower legs.