Table 3.
Independent Predictors of Recovery Trajectory Selected with Each Variable Selection Model
| Predictors of recovery trajectory: All 7 classes | Predictors of recovery trajectory: B1 (rapid recovery) vs. B2 (gradual recovery) only | |||||
|---|---|---|---|---|---|---|
| Backward | Forward | Step | Backward | Forward | Step | |
| Demographics | ||||||
| Age | A | *A | ||||
| Sex | ||||||
| Race | *A | |||||
| Ethnicity | A | * | * | |||
| Living situation | ||||||
| Education | A | |||||
| Employment | ** | A | ||||
| Pre-existing canditions | ||||||
| Cardiovascular disease | ||||||
| Hypertension | ||||||
| Diabetes | **A | **A | **A | |||
| Psychiatric disorder | *A | * | ||||
| Treatment | ||||||
| Citicoline treatment | ||||||
| Site | ** | |||||
| TBI/acute medical characteristics | ||||||
| GCS | A | **A | **A | **A | **A | **A |
| PTA | **A | **A | **A | |||
| TBI mechanism | A | |||||
| Major extracranial injury | **A | **A | **A | A | ||
| Hypotension | ||||||
| Hypoxia | ||||||
| INR | ||||||
| Hemoglobin | ** | |||||
| Glucose | ||||||
| Baseline head CT | ||||||
| Midline shift | ||||||
| Mesencephalic cisterns | *A | |||||
| SAH | A | |||||
| IPH | A | |||||
| SDH | *A | ** | ||||
| EDH | ||||||
Stopping rules for each model are designated as follows: *p < 0.1; **p < 0.05 (all variables selected with stopping rule of p < 0.05 were also selected with stopping rule of p < 0.1); A, Akaike information criterion (AIC).
PMH, past medical history; GCS, Glasgow Coma Scale; PTA, post-traumatic amnesia; TBI, traumatic brain injury; INR, international normalized ratio; SAH, subarachnoid hemorrhage; IPH, intraparenchymal hemorrhage; SDH, subdural hemorrhage; EDH, epidural hemorrhage.