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Severe (grade 3 or 4) toxicities by gemcitabine-containing regimens
| Antibiotics-untreated group (n=93) | Antibiotics-treated group (n=76) | |
|---|---|---|
| Leukopenia | 14 (15.1) | 36 (47.4) |
| Neutropenia | 27 (29.0) | 42 (55.3) |
| Anemia | 15 (16.1) | 12 (15.8) |
| Thrombocytopenia | 10 (10.7) | 7 (9.2) |
| Febrile neutropenia | 0 (0.0) | 2 (2.6) |
| Elevated AST/ALT | 7 (7.5) | 6 (7.9) |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase.
