Table 2. Hazard ratios (HRs) and 95% confidential intervals (CIs) for recurrence free survival (RFS).
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
HRs (95% CI) | P value | HRs (95% CI) | P value | |
Age | <0.001 | <0.001 | ||
>35 | 1 | 1 | ||
≤35 | 0.355(0.227–0.555) | 0.416(0.256–0.674) | ||
T stage | 0.001 | 0.514 | ||
1 | 1 | 1 | ||
2 | 1.5661.005–2.442) | 0.048 | 1.293(0.801–2.085) | 0.293 |
3 | 4.196(2.162–8.142) | <0.001 | 1.740(0.833–3.635) | 0.141 |
N stage | <0.001 | <0.001 | ||
0 | 1 | 1 | ||
1 | 1.694(1.066–2.690) | 0.026 | 1.339(0.809–2.214) | 0.256 |
2 | 3.702(2.111–6.492) | <0.001 | 2.938(1.601–5.393) | 0.001 |
3 | 5.313(3.057–9.232) | <0.001 | 3.969(2.068–7.619) | <0.001 |
LVI | <0.001 | 0.272 | ||
Negative | 1 | 1 | ||
Positive | 2.377(1.468–3.848) | 1.349(0.791–2.300) | ||
HG | 0.990 | |||
I and II | 1 | |||
III | 1.001(0.825–1.216) | |||
A20 | <0.001 | <0.001 | ||
Low | 1 | 1 | ||
High | 2.672(1.710–4.175) | 2.324(1.446–3.736) | ||
ER | 0.535 | |||
Negative | 1 | |||
Positive | 1.127(0.772–1.646) | |||
PR | 0.535 | |||
Negative | 1 | |||
Positive | 0.887(0.607–1.296) | |||
HER2 | 0.862 | |||
Negative | 1 | |||
Positive | 0.954(0.560–1.624) | |||
TNBC vs non-TNBC | 0.842 | |||
non-TNBC | 1 | |||
TNBC | 1.042(0.692–1.570) |
LVI, Lymphovascular invasion; HG, histologic grade; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor-2; TNBC, triple negative breast cancer