Table 3. Hazard ratios (HRs) and 95% confidential intervals (CIs) for Overall survival (OS).
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Age | 0.001 | 0.042 | ||
>35 | 1 | 1 | ||
≤35 | 0.429(0.260–0.708) | 0.536(0.325–0.978) | ||
T stage | <0.001 | 0.073 | ||
1 | 1 | 1 | ||
2 | 1.677(0.995–2.828) | 0.052 | 1.340(0.763–2.355) | |
3 | 5.751(2.836–11.662) | <0.001 | 2.123(0.955–4.718) | |
N stage | <0.001 | <0.001 | ||
0 | 1 | 1 | ||
1 | 1.460(0.845–2.524) | 0.175 | 1.128(0.619–2.053) | |
2 | 3.847(2.086–7.093) | <0.001 | 2.894(1.483–5.648) | |
3 | 6.566(3.672–11.741) | <0.001 | 4.067(2.027–8.162) | |
LVI | <0.001 | 0.116 | ||
Negative | 1 | 1 | ||
Positive | 3.079(1.833–5.172) | 1.595(0.891–2.856) | ||
HG | 0.492 | |||
I and II | 1 | |||
III | 1.080(0.867–1.344) | |||
A20 | <0.001 | <0.001 | ||
Low | 1 | 1 | ||
High | 2.906(1.801–4.690) | 2.629(1.585–4.361) | ||
ER | 0.292 | |||
Negative | 1 | |||
Positive | 0.793(0.515–1.221) | |||
PR | 0.330 | |||
Negative | 1 | |||
Positive | 0.808(0.526–1.241) | |||
HER2 | 0.831 | |||
Negative | 1 | |||
Positive | 0.934(0.497–1.754) | |||
TNBC vs non-TNBC | 0.857 | |||
Non-TNBC | 1 | |||
TNBC | 1.045(0.645–1.693) |
LVI, Lymphovascular invasion; HG, histologic grade; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor-2; TNBC, triple negative breast cancer