Fig 8. Schematic representation of PaRid & FPR1 developmental pathways during sexual development.

FPR1, a MATα-HMG transcription factor is essential to fertilization and development of fruiting bodies. This mating type protein can act either as an activator or as a repressor. This study established that PaRid shares part of the FPR1 positive regulatory circuit, which is at work after fertilization to build the fructification and to form the dikaryotic cells. As the methyltransferase activity is required for PaRid function, we hypothesized that PaRid might repress a repressor or alternatively might activate an activator of the FPR1 regulatory circuit [118]. Solid black arrow is indicative of activation. Dashed T-line is indicative of repression. Solid grey arrow represents the sexual development time line.