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. 2019 Aug 14;13(8):e0007650. doi: 10.1371/journal.pntd.0007650

Fig 12. Expression of antimicrobial genes following stimulation of 3-D models with different Salmonella strains.

Fig 12

3-D organotypic models were exposed, or not, to either Salmonella enterica serovar Paratyphi A (PA), Paratyphi B (PB), or Typhi (ST) strains. After 4 hours, constructs were collected and used to measure gene expression by qRT-PCR. Data are shown as unsupervised clustergrams displaying hierarchical clustering of the dataset as a heat map. Geometric mean values of 2 independent experiments, each with 2 replicates are reported. Genes detected by the Antimicrobial Responses RT2 Profiler PCR Array. (A) Toll-Like Receptor (TLR) signaling. (B) Downstream signaling of antibacterial responses. (C) NOD-Like Receptor (NLR) signaling. (D) Apoptosis signaling.