Table 2.

Admitting Diagnoses and Therapies Received

Admitting Diagnoses	Compatible (n = 342)	Major Incompatibility ( n = 133)	Minor Incompatibility (n = 28)	p-values
Reason for PICU Admission, n (%):
Organ Failure
Respiratory insufficiency/failure	141 (41)	53 (40)	10 (36)	0.83
Renal failure	32 (9)	16 (12)	1 (4)	0.36
Hepatic failure	18 (5)	7 (5)	1 (4)	0.93
Shock
Septic shock	88 (26)	18 (14)	7 (25)	0.02
Hemorrhagic shock	21 (6)	7 (5)	1 (4)	0.82
Other shock	15 (4)	6 (5)	0 (0)	0.52
Trauma	8 (2)	5 (4)	0 (0)	0.46
Cardiac
Cardiac surgery-bypass	39 (11)	18 (14)	3 (11)	0.80
Cardiac surgery-no bypass	6 (2)	4 (3)	0 (0)	0.50
Cardiac – non-surgical	27 (8)	16 (12)	6 (21)	0.04
Post-operative
Emergency surgery	14 (4)	7 (5)	0 (0)	0.45
Elective surgery	14 (4)	10 (8)	0 (0)	0.14
Post-op liver transplant	10 (3)	2 (2)	1 (4)	0.64
Neurosurgical
Traumatic brain injury	5 (2)	3 (2)	0 (0)	0.65
Intracranial bleed/intracranial hypertension	9 (3)	3 (2)	0 (0)	0.68
Neurologic
Seizure	9 (3)	2 (2)	2 (7)	0.23
Encephalopathy	29 (9)	8 (6)	2 (7)	0.66
Meningitis	4 (1)	1 (1)	0 (0)	0.72
Veno-occlusive disease	4 (1)	2 (2)	0 (0)	0.80
New leukemia/hyperleukocytosis	14 (4)	2 (2)	2 (7)	0.23
Hemophagocytic lymphohistiocytosis	5 (2)	1 (1)	0 (0)	0.68
Other	25 (7)	6 (5)	4 (14)	0.16
Therapies Received, n (%)
Medications
Milrinone	55 (16)	26 (20)	4 (14)	0.62
Non-steroidal anti-inflammatories	5 (2)	5 (4)	0 (0)	0.20
Aspirin	9 (3)	4 (3)	0 (0)	0.66
Devices
Extracorporeal Membrane Oxygenation	60 (18)	18 (14)	7 (25)	0.29
Continuous renal replacement therapy	31 (9)	18 (14)	3 (11)	0.36
Intermittent hemodialysis	3 (1)	3 (2)	0 (0)	0.54
Molecular adsorbent circulating system	2 (0.6)	3 (2)	0 (0)	0.26
Median (IQR) dose (mL/kg) platelet transfusions received prior to enrollment	30 (12–77)	58 (22–108)	19 (11–29)	0.06

p-values calculated using Chi-squared for large samples and Fisher’s Exact for small samples