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. 2019 Aug 14;11(15):5744–5756. doi: 10.18632/aging.102157

Figure 3.

Figure 3

MiR-627-3p inhibits osteosarcoma cell proliferation. (A, B) MTT assays showing cell proliferation after transfection with miR-627-3p mimic/inhibitor in HOS, MG63 and MG63/dox cells. Data are the mean ± SEM. ** P< 0.05 vs. control group. (C, D) Colony formation assays showing HOS and MG63 cell proliferation after transfection with miR-627-3p mimic/inhibitor. Data are the mean ± SEM. ** P< 0.05 vs. control group. (E, F) AV-PI assay showing cell apoptosis among HOS cells transfected with miR-627-3p mimic/inhibitor. (G–J) Western blot and real-time PCR analyses of Cyclin D1 expression in osteosarcoma cells transfected with miR-627-3p mimic/inhibitor. Data are the mean ± SEM. ** P< 0.05.