Table 1. Demographic information for frailty cohorts.

A	RNA sequencing cohort
	Non-frail	Pre-frail/Frail
n	8	8
Age (mean (sd))	48.09 (1.21)	47.85 (1.84)
Sex = Women (%)	4 (50.0)	4 (50.0)
Race = White (%)	4 (50.0)	4 (50.0)
PovStat = Below (%)	2 (25.0)	4 (50.0)
B	Validation cohort
Validation cohort
	B:Non-frail	W:Non-frail	B:Frail	W:Frail
n	13	13	13	13
Age (mean (sd))	47.51 (1.59)	47.23 (1.26)	47.04 (1.62)	47.58 (1.80)
Sex = Women (%)	7 (53.8)	6 (46.2)	7 (53.8)	6 (46.2)
PovStat = Below (%)	6 (46.2)	3 (23.1)	8 (61.5)	5 (38.5)