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. 2019 Aug 15;11(15):5807–5816. doi: 10.18632/aging.102170

Table 4. Risk of first stroke or ischemic stroke related to HVA vs Non-HVA.

Outcome HR(95%CI) p value
Stroke
Model 1 0.21(0.12–0.36) < 0.001
Model 2 0.23(0.13–0.39) < 0.001
Model 3 0.23(0.14–0.40) < 0.001
Model 4 0.32(0.18–0.56) < 0.001
Ischemic stroke
Model 1 0.22(0.12–0.37) <0.001
Model 2 0.23(0.14–0.41) <0.001
Model 3 0.24(0.14–0.42) <0.001
Model 4 0.32(0.18–0.58) <0.001

Model 1: Adjusted for age and sex.

Model 2: Model 1 + adjustment for body mass index, smoking, alcohol drinking, physical activity, history of diabetes, history of hyperlipidemia.

Model 3: Model 2 + adjustment for monthly income, education level, fast blood glucose, total cholesterol, low-density lipoprotein cholesterol, high-sensitive C-reactive protein, use of antidiabetic and lipid-lowering medications.

Model 4: Model 3 + adjustment for systolic blood pressure

Abbreviations: HVA: healthy vascular aging; HR: hazard ratio; CI: confidence interval.