Table 2. Peak SNPs associated with annualized percent change of CSF Aβ₄₂.

CHR	SNP	Gene	Position	Function	A1/2	MAF	βa	P value
16	rs13333659	CBFA2T3	89038880	Intron	T/G	0.177	−0.034	2.24×10−9
16	rs57706252	CBFA2T3	89030609	Intron	C/T	0.167	−0.029	1.09×10−6
9	rs35878400	TRPM6	77482795	Intron	T/C	0.273	0.024	1.87×10−6
8	rs6987191	/	138246221	/	C/T	0.131	−0.031	6.99×10−6
17	rs113685315	RBFOX3	77390248	Intron	A/G	0.162	0.025	8.31×10−6
3	rs55732227	PDZRN3	73611629	Intron	T/A	0.309	−0.020	9.86×10−6

Abbreviations: CHR = chromosome; SNP = single nucleotide polymorphism; MAF = minor allele frequency; A1/2 = minor allele/major allele.

^a β effect size from GWAS means the annualized percent change of CSF Aβ₄₂ conferred by one copy of the minor allele.