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. 2019 Aug 5;11(15):5300–5318. doi: 10.18632/aging.102092

Figure 8.

Figure 8

MSCs-derived exosomal miR-199a inhibits the proliferation, invasion and migration of glioma cells. (AB) the invasion ability of U251 cells, assessed by Transwell assay (Scale bar = 50 μM). (CD) the migration ability of U251 cells, measured by scratch test (Scale bar = 100 μM). (EF) the proliferation ability of U251 cells, evaluated by EdU assay (Scale bar = 50 μM). * p < 0.05. The results were measurement data, presented as mean ± standard deviation. Paired t-test was used for the analysis. The experiment was repeated three times. MSCs-mimic-NC, glioma cells co-cultured with mesenchymal stem cells and transfected with mimic-negative control; MSCs-miR-199a mimic, glioma cells co-cultured with mesenchymal stem cells and transfected with miR-199a mimic.