Table 3. Univariate and multivariate analysis of the correlation of CASC19 expression with OS among GC patients.
| Variables | Univariate analysis | Multivariate analysis | ||||
| HR | 95% CI | P | HR | 95% CI | P | |
| Age (years) | ||||||
| <65 years | Ref. | Ref. | ||||
| ≥65 years | 1.542 | 1.085-2.192 | 0.016 | 1.585 | 1.096-2.291 | 0.014 |
| Gender | ||||||
| Male | Ref. | |||||
| Female | 0.857 | 0.599-1.226 | 0.399 | |||
| Histology | ||||||
| Well | Ref. | |||||
| Moderate or poor | 1.931 | 0.477-7.814 | 0.356 | |||
| Pathologic TNM stage | ||||||
| I-II | Ref. | Ref. | ||||
| III-IV | 1.699 | 1.175-2.456 | 0.005 | 1.501 | 0.902-2.499 | 0.118 |
| Pathologic T stage | ||||||
| T2 | Ref. | |||||
| T3-T4 | 1.470 | 0.955-2.262 | 0.080 | |||
| Metastatic lymph nodes | ||||||
| Negative | Ref. | |||||
| Positive | 1.573 | 1.031-2.400 | 0.036 | 1.123 | 0.623-2.024 | 0.700 |
| Distant metastasis | ||||||
| Negative | Ref. | |||||
| Positive | 1.760 | 0.945-3.279 | 0.074 | |||
| CASC19 expression | ||||||
| Low | Ref. | Ref. | ||||
| High | 1.637 | 1.096-2.447 | 0.016 | 1.524 | 1.003-2.316 | 0.049 |
Bold values indicate P < 0.05.