. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: Alzheimer Dis Assoc Disord. 2019 Jul-Sep;33(3):260–265. doi: 10.1097/WAD.0000000000000317

Table 1.

Patient Characteristics by Diagnostic Group

	bvFTH		nfvPPA		svPPA		CBS		PSP-S		AD		Statistics and P value
	n	Mean (SD)	n	Mean (SD)	n	Mean (SD)	n	Mean (SD)	n	Mean (SD)	n	Mean (SD)

Age	156	60.94 (8.50)^b,d,e,f,	38	66.47 (9.93)^a	72	63.50 (6.58)^e	49	65.51 (8.57)^a	45	68.82 (7.29)^a,c	123	66.93 (10.78)^a	F(1,5)= 9.59, p<.001
Gender (M/F)	156	94/62	38	14/24	72	36/36	49	21/28	45	22/23	123	56/67	χ²(5, N=483)=11.18, p<.05
MMSE	152	21.84 (7.51)^e	35	23.53 (7.32)^f	69	22.17 (7.54)	46	24.33 (4.99)^f	43	25.42 (4.73)^a,f	111	20.80 (5.98)^b,d,e	F(1,5)= 4.77, p<.001
CDR	152	1.33 (0.74)^b,c,d,e,f	36	0.51 (0.41)^a,f	72	0.78 (0.52)^a	44	0.72 (0.59)^a	43	0.87 (0.67)^a	118	0.89 (0.42)^a,b	F(1,5)= 19.32, p<.001
CDR-SB	152	7.50 (3.63) ^b,c,d,e,f	36	2.17 (2.04)^a,c,e,f	72	4.34 (3.12)^a,b	44	3.57 (3.29)^a	43	4.84 (3.78)^a,b	118	4.95 (2.50)^a,b	F(1,5)= 26.02, p<.001
NPI	149	45.76 (21.39) ^b,c,d,e,f	33	12.58 (13.68)^a,c,e	69	31.49 (19.95)^a,b,d,f	45	22.96 (16.47)^a,c	42	29.26 (18.80)^a,b	45	19.07 (16.30)^a,c	F(1,5)= 29.27, p<.001
IRI-EC	134	18.78 (6.53) ^b,c,d,e,f	34	25.47 (5.02)^a	64	22.92 (7.68)^a,f	41	23.78 (7.07)^a	40	23.95 (7.07)^a	110	26.79 (5.16)^a,c	F(1,5)= 20.69, p<.001
IRI-PT	133	12.21 (5.34) ^b,c,d,e,f	34	21.44 (5.44)^a,c	65	15.42 (6.72)^a,b,e,e	41	19.27 (6.32)^a	41	20.29 (7.13)^a,c,	110	19.05 (6.14)^a,c	F(1,5)= 26.25, p<.001

All variables were derived from the first available time point. Continuous variables compared by ANOVA with post-hoc pairwise Dunnett’s T3 tests. Gender compared by chi square.

p <.05 versus bvFTD group

p <.05 versus nfvPPA group

p <.05 versus svPPA group

p <.05 versus CBS group

p <.05 versus PSP-S group

p <.05 versus AD group.

MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating; CDR-SB, CDR sum of boxes; NPI, Neuropsychiatric Inventory; IRI, Interpersonal Reactivity Index; EC, empathic concern; PT, perspective taking.