Table 2.
Scoring System for DIC Established by the JMHW.56 a
Score | |||
---|---|---|---|
Criteria | Points | ||
1. Underlying disease | (+) | 1 | |
(−) | 0 | ||
2. Symptoms | (1) Bleeding tendency | (+) | 1 |
(−) | 0 | ||
(2) Symptom caused by organ dysfunction | (+) | 1 | |
(−) | 0 | ||
3. Laboratory data | (1) Plasma FDP (µg/mL) | ≥40 | 3 |
20-40 | 2 | ||
10-20 | 1 | ||
<10 | 0 | ||
(2) Platelet count (× 109/L) | ≤50 | 3 | |
50-80 | 2 | ||
80-120 | 1 | ||
>120 | 0 | ||
(3) Plasma fibrinogen (mg/dL) | ≤100 | 2 | |
100-150 | 1 | ||
>150 | 0 | ||
(4) Prothrombin time ratio (PT of patient/PT of control) | ≥1.67 | 2 | |
1.25-1.67 | 1 | ||
<1.25 | 0 | ||
Supplemental Data | |||
(1) Detection of soluble fibrin monomer | |||
(2) Increase in d-dimers | |||
(3) Increase in thrombin–antithrombin complex | |||
(4) Increase plasmin–antiplasmin complex | |||
(5) Exacerbation of FDP, platelet, fibrinogen within several days | |||
(6) Improvement of data with anticoagulant therapy | |||
Interpretation | |||
1. Definite DIC | (1) Patients who do not have leukemia, pernicious anemia, liver cirrhosis, or who are not under cancer chemotherapy | More than 7 or 6 points with more than 2 of supplemental data | |
(2) Patients who have leukemia, pernicious anemia, or who are under cancer chemotherapy points for bleeding tendency and platelet are not included | More than 4 or 3 points with more than 2 of supplemental data | ||
(3) Patients who have liver cirrhosis | More than 10 or 9 points with more than 2 of supplemental data | ||
2. Probable DIC | (1) Patients who do not have leukemia, pernicious anemia, liver cirrhosis, or who are not under cancer chemotherapy | 6 points | |
(2) Patients who have leukemia, pernicious anemia, or who are under cancer chemotherapy points for bleeding tendency and platelet are not included | 3 points | ||
(3) Patients who have liver cirrhosis | 9 points |