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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Reprod Toxicol. 2019 Feb 26;92:138–147. doi: 10.1016/j.reprotox.2019.02.010

Figure 2. Methylation differences by p,p’-DDE in CCDC85A, and CYP1A1.

Figure 2.

The boxplot displays the distribution of CpG methylation values (percent) by different p,p’-DDE exposure group (low exposure, ≤ 35.23 μg/L; median exposure, > 35.23–58.49 μg/L; high exposure, > 58.49 μg/L).) in 2 gene regions (CCDC85A and CYP1A1) examined. The middle bold line represents the median methylation. Each dot represents the methylation value of each samples. The distribution of percentage of CCDC85A methylation (left) by each p,p’-DDE exposure group: low exposure (median: 34.7%, Q1-Q3=(30.7%, 38.5%), Min-Max(22.5%, 48.3%)); median exposure (median:34.2%, Q1-Q3=(30.7.0%, 38.9%), Min-Max=(21.0%, 49.9%)); high exposure (median: 36.4%, Q1-Q3=(32.3%, 40.7%), Min-Max=(19.8%, 50.9%)). The distribution of percentage of CYP1A1 methylation (right) by each p,p’-DDE exposure group: low exposure (median: 50.0%, Q1-Q3=(38.1%, 58.2%), Min-Max= (16.8%, 76.1%); median exposure (median: 51.8%, Q1-Q3=(41.0%, 58.3%), Min-Max=(9.5%, 82.5%)); high exposure (median:55.0%, Q1-Q3=(45.4%, 64.6%), Min-Max=(20.2%, 79.6%)).