Table 4.

Distribution of methylation levels in 30 genes by o,p’-DDT exposure of daughters in the Child Health and Development Studies Pregnancy Cohort

	o,p’-DDT ≤0.42, μg/L		o,p’-DDT: 0.43–0.72, μg/L		o,p’-DDT >0.72, μg/L
Gene	Median	IQR	Median	IQR	Median	IQR	P.value
ADRB1	24.3	8.9	24.8	8.6	25.1	11.6	0.43
ARHGEF7	45.5	8.6	44.4	9.3	44.6	9.2	0.90
BRCA1	81.9	12.1	81.2	12.8	82.3	10.5	0.97
CCDC85A	34.3	8.0	34.8	8.0	36.4	8.5	0.01
CCNL1	0.3	0.8	0.3	0.7	0.3	0.6	0.90
CDH1	7.4	2.2	7.1	3.0	7.9	2.9	0.05
CELF4	56.5	10.0	56.3	12.6	55.0	12.4	0.40
chr11	8.0	4.4	8.2	4.7	7.5	5.8	0.90
chr12	78.6	5.0	78.1	5.2	78.1	4.9	0.95
chr16	81.6	5.5	82.3	6.2	81.9	5.8	0.17
chr4	81.4	8.6	81.5	9.6	82.1	8.3	0.88
CYP1A1	50.3	19.7	51.9	16.4	54.0	14.5	0.05
DLGAP2	97.1	1.0	97.1	1.2	97.0	1.3	0.75
ESR1	55.0	19.2	54.9	22.1	55.2	21.1	0.98
GAB2	97.0	2.7	96.9	2.7	97.1	3.5	0.96
GNA12	36.0	20.8	37.8	23.8	42.4	26.8	0.35
IGF1	83.2	5.5	83.4	7.2	83.1	9.5	0.92
MCHR2	13.2	3.5	12.7	4.5	13.4	3.9	0.37
OBSCN	92.7	1.8	92.5	1.7	91.9	2.1	0.05
PCDHGB1	40.1	7.7	40.2	7.9	40.5	9.4	0.66
PEX14	65.6	7.2	67.8	7.5	66.5	8.1	0.37
RAD51L1	98.1	1.8	98.3	1.3	98.1	1.8	0.33
RECQL4	86.6	4.6	87.8	4.0	87.5	3.9	0.03
SLC39A14	87.2	8.6	87.6	10.1	87.2	15.9	0.45
SLC6A3	73.5	5.2	74.5	6.2	74.5	5.1	0.13
TCF7L2	52.5	13.0	49.6	15.8	51.4	16.2	0.28
TERT	96.7	2.8	96.6	2.8	96.8	2.8	0.96
XRCC3	79.7	3.2	79.7	3.7	79.7	4.5	0.81
ZFPM2	43.3	11.2	44.6	11.9	48.9	13.5	0.01
ZNF483	36.1	3.6	35.5	3.1	35.9	4.0	0.23

p value of Kruskal-Wallis test

IQR: The interquartile range