Table 3.
CSF standard parameter findings of patients with leptomeningeal metastasis.
| Characteristics | Pleocytosis (≥5 cells/μl) | Elevated protein (≥500 mg/l) | Elevated Lactate (≥3.5 mmol/l) | Blood-CSF-barrier dysfunction |
|---|---|---|---|---|
| Solid malignancies (n = 76) |
79% | 82% | 68% | 80% |
| Breast cancer (n = 26) |
73% | 88% | 77% | 91% |
| Lung cancer (n = 25) |
80% | 86% | 55% | 77% |
| Gastrointestinal cancer (n = 12) |
75% | 58% | 70% | 58% |
| Other malignancies (n = 13) |
92% | 83% | 73% | 77% |
| Hematological malignancies (n = 37) |
92% | 89% | 48% | 92% |
| Lymphoid malignancies (n = 31) |
90% | 87% | 56% | 90% |
| Myeloid malignancies (n = 6) |
100% | 100% | 17% | 100% |
| p value | 0.03 | 0.57 | 0.08 | 0.16 |