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. 2019 Aug 20;9:783. doi: 10.3389/fonc.2019.00783

Table 2.

Patients characteristics among the 35 studies included in this review.

References Cancer type Cancer stage Metastasis Treatment Time since diagnosis Age at diagnosis Age Sex
Andrykowski et al. (18) Breast 0-IIIA Not specified Adjuvant therapy: chemotherapy or radiotherapy; Breast surgery: lumpectomy or astectomy Not specified Mean: 54.7 ± 10.6 Not specified All female
Anota et al. (19) Breast Not specified 301 patients had a lymph node dissection Chemotherapy; hormone therapy; radiotherapy; surgery (mastectomy) Diagnosed between February 2006 and February 2008 Not specified Mean: 58.4 ± 11 All female
Bernhard et al. (20) Colon pT1-4 pN>0 M0 and pT3-4 pN0 M0 Not specified Chemotherapy; surgery Not specified Not specified Median: 62 Range: 27–88 59% male
Brinksma et al. (21) Hematologic; brain tumor; solid tumor Not specified Not specified Not specified Not specified Not specified Child report Mean: 14 Range: 8–17 Parent report Mean: 9 Range: 2–17 Child report: 54% female; Parent report: 55% female
Broberger et al. (22) Lung Not specified Not specified Not specified 3-month follow-up: 119 days 6-month follow-up: 219 days Not specified Mean: 64 ± 10 Range: 47–95 49% female
Dabakuyo et al. (23) Breast AJCC stage: 0–4 163 patients had a lymph node biopsy Chemotherapy; hormone therapy; radiotherapy; surgery (mastectomy) Not specified Divided into two groups: <65 (younger); >65 (older) Mean: 58.4 ± 11 All female
Echteld et al. (24) Lung; colorectal: urogenital; breast; melanoma; sarcoma; other Not specified Not specified Not specified Not specified Not specified Mean: 55.3 Range: 27–80 69% female
Gerlich et al. (25) Prostate TNM classification: T1–T4 Not specified Radiotherapy; surgery Not specified Not specified Mean: 64.7 ± 7.1 All male
Hagedoorn et al. (26) Breast; gastrointestinal tumors; lymphomas; genitourinary; lung; gynecological Not specified Yes, in 140 patients Not specified Not specified Not specified Mean: 50.5 ± 14.4 Range: 19–80 55% female
Hamidou et al. (27) Breast AJCC stage: 0–4 283 patients had LND Chemotherapy; hormone therapy; radiotherapy; surgery Not specified Not specified Mean: 58 ± 11.1 All female
Hinz et al. (28) Prostate; kidney; bladder; testicles; penis; renal pelvis I-IV Not specified Chemotherapy; hormone therapy; radiotherapy; surgery Mean: 112.9 ± 294 Not specified Mean: 63.7 ± 8.3 All male
Hinz (29) Breast Not specified Not specified Chemotherapy; radiotherapy; hormone therapy At least 6 months, to over 5 years Not specified Mean: 66.1 ± 9.3 All female
Ito et al. (30) Rectal TNM classification: 1–4 TNM staging N (%): I-IIIb: 12 (92); IV: 1 (8) Surgery Not specified Not specified Mean: 66.9 ± 11.3 62% male
Jakola et al. (31) Glioma WHO grade II-IV Not specified Radiotherapy; surgery Not specified Not specified Mean: 49 ± 15 26% female
Jansen et al. (32) Breast Early-stage Not specified Surgery (lumpectomy or mastectomy); radiotherapy Not specified Not specified Mean: 55 ± 10 All female
Jorngarden et al. (33) CNS tumor; Ewing sarcoma; leukemia; lymphoma; osteosarcoma; other Not specified Not specified Chemotherapy Not specified Mean: 15.7; 13–15 years (N = 35); 16–19 years (N = 21) Not specified 57% male
King-Kallimanis et al. (34) Lung; pancreatic; esophageal; cervical Not specified No Surgery Not specified Not specified Mean: 57.3 ± 14.2 51.49% male
Korfage et al. (35) Prostate Not specified Not specified Active surveillance; brachytherapy; external radiotherapy; hormonal treatment; radical prostatectomy Beginning of study Not specified Mean: 67.3 ± 4.4 All male
Kvam et al. (14) Multiple myeloma Not specified Not specified ASCT; MP ± Thalidomide; Thalidomide; Velcade Not specified Not specified Median: 66 Range: 36–89 54% male
Oort et al. (36) Lung; pancreas; esophageal; cervical Not specified Not specified Surgery Not specified Not specified Mean: 57.5 ± 14.1 51% male
Ousmen et al. (37) Breast AJCC stage: 0–4 301 patients had LND Chemotherapy; hormone therapy; radiotherapy; surgery Not specified Not specified Mean: 58.4 ± 11 All female
Rees et al. (38) Prostate TNM classification: T2–T4 Yes, distant metastases identified in 19 patients Active surveillance; hormone therapy; radiotherapy Not specified Not specified Mean: 72.8 ± 8.5 All male
Salmon et al. (39) Breast I-III No Surgery; chemotherapy; radiotherapy; hormone therapy Not specified Not specified Mean: 57 ± 10.4 All female
Sharpe et al. (13) Multiple, but primarily lung and colorectal Not specified Yes, all patients had metastatic cancer Chemotherapy; radiotherapy; combination; other Metastatic cancer in previous 3 months before the study Not specified Mean: 64 ± 8.6 49% male
Sharpley and Christie (40) Breast Not specified Not specified Not specified Average: 2 years 8 months Not specified Mean: 58.76 Range: 26–85 All female
Sprangers et al. (17) Breast; lung; prostate; Hodgkin Not specified Not specified Radiotherapy Not specified Not specified Median: 63 Range: 28–89 60% female
Tessier et al. (41) Breast TNM classification: I or II No Not specified First survey distributed 1 month following diagnosis Not specified Mean: 53 All female
Traa et al. (42) Colorectal Not specified Non-curatively treated metastases at baseline excluded Chemotherapy; radiotherapy; surgery Not specified Not specified Mean: 62 ± 8.6 71.2% male
Verdam et al. (43) Breast; prostate; lung; other Not specified Yes, all with bone metastases from a solid tumor Not specified Not specified Not specified Mean: 64.87 46% female
Verdam et al. (44) Breast; colorectal; lung; other Not specified Yes in 40% of patients Chemotherapy; radiotherapy Not specified Not specified Mean: 57 ± 12.1 41% male
Visser et al. (45) Head and neck; gastrointestinal; gynecological; lung; breast; genitourinary tract; hematological malignancies; other Not specified Not specified Radiotherapy Not specified Not specified Mean: 64 ± 13 58% male
Visser et al. (36) Lung; periampullary; esophageal; cervical Not specified Not specified Surgery Not specified Not specified Mean: 57.7 ± 14.1 Range: 27–83 51% male
Visser et al. (4) Lung; periampullary; esophageal; cervical Not specified Not specified Surgery Not specified Not specified Mean: 57.28 ± 14.2 51% male
von Blackenburg et al. (47) Breast; lung; urologic; digestive; Gynecologic; other Not specified Yes in 29 patients (33.7%) Chemotherapy; radiotherapy; Surgery Not specified Not specified Mean: 52.5 ± 8.1 Range: 31–65 53.5% female
Westerman et al. (48) Lung Not specified Not specified Chemotherapy Not specified Not specified Mean: 58.7 Range: 46–72 47.8% male

AJCC, American Joint Committee on Cancer; ASCT, autologous stem cell transportation; CNS, central nervous system; LND, lymph node dissection; MP, Melphalan and Prednisone; TNM, Tumor Node Metastasis; WHO, World Health Organization.