Skip to main content
. 2019 Aug 20;9:783. doi: 10.3389/fonc.2019.00783

Table 4.

Response Shift indicators in studies assessing QoL among cancer patients and methods used to assess Response Shift.

References Cancer type Methods used to assess response shift Global QoL Physical functioning Role functioning Emotional functioning Cognitive functioning Sexual functioning Social functioning Fatigue Pain MH Other sig. results
Andrykowski et al. (18) Breast Then-test O O O O O O O S (Average fatigue CT or RT: 0.35 SD Average fatigue CT + RT: 0.52 SD) O O O
Anota et al. (19) Breast Then-test S (at 3 months; −0.21) S (at 6 months; 0.31) S (at 3 and 6 months;−0.32, 0.30) S (after hospitalization and 3 months; 0.21, 0.27) NS NS S (at 3 and 6 months; −0.27, 0.22) S (at 6 month; −0.43) S (at 6 months; −0.23) O Nausea and vomiting- NS; Dyspnea—NS; Insomnia—S (at 3 and 6 months) −0.22, −0.18; Appetite loss—NS; Constipation—NS; Diarrhea—NS; Financial difficulties—NS; Body image—S (at 3 and 6 months) 0.48, 0.25; Future perspective—S (after hospitalization and 3 months) 0.24, 0.23; STSE—S (at 6 months) −0.24; Breast symptoms—S (at 6 months) −0.31; Arm symptoms—NS; Hair loss—NS
Bernhard et al. (20) Colon Then-test NS—surgery NS–surgery O O O O O O O O S–subjective health
Brinksma et al. (21) Hematologic; brain tumor; solid tumor Then-test S–for children (−0.74) and parents (−0.3) NS O NS NS O NS O O O O
Broberger et al. (22) Lung Then-test S (3 months, 0.40; 6 months, 0.70) S (3 months, 0.23) O O O O O S (3 months, 0.29) O O O
Dabakuyo et al. (23) Breast Then-test, Ideal scale, Successive comparison scale S O O S S O O S O O Insomnia—S, Appetite loss—NS, Diarrhea—NS, Future Perspectives—NS, Systemic therapy side effects—S
Echteld et al. (24) Lung; colorectal: urogenital; breast; melanoma; sarcoma; other Pre-test, post-test S (0.60) O O O O O O S (0.20) S (0.66) O O
Gerlich et al. (25) Prostate Then-test O S (−0.44) S (−0.47) S (0.17) S (−0.13) O S (−0.35) O O O O
Hagedoorn et al. (26) Breast; gastrointestinal tumors; lymphomas; Genitourinary; lung; gynecological Pre-test, post-test S S O S O O O O O O O
Hamidou et al. (27) Breast Then-test NS S S S S S S S S O Nausea—S, Dyspnea—S, Insomnia–S, Appetite Loss—S, Diarrhea–NS, Body Image–S, Future Perspectives–NS, Systemic Therapy Side Effects—S, Breast Symptoms–S, Arm Symptoms–S
Hinz et al. (28) Prostate; kidney; bladder; testicles; penis; renal pelvis Then-test O O O O O O O O O S (anxiety, 0.26; depression 0.30) Distress–NS, Health dissatisfaction—S
Hinz (29) Breast Vignettes Vignette A: S NS NS NS NS NS NS NS NS NS NS
Ito et al. (30) Rectal Then-test NS NS NS NS O NS NS NS S NS O
Jakola et al. (31) Glioma Then-test NS O O O O O O O O O O
Jansen et al. (32) Breast Then-test S S O O O O O S O O Psychological well-being–NS
Jorngarden et al. (33) CNS tumor; Ewing sarcoma; leukemia; lymphoma; osteosarcoma; other Pre-test, post-test O O O O O O O O O S (Anxiety, depression, and mental health) Vitality—S
King-Kallimanis et al. (34) Lung; pancreas; esophageal; cervical Pre-test, post-test with SEM models S NS NS NS O O O O S NS Vitality- NS
Korfage et al. (35) Prostate Then-test, vignettes S (7 month follow up, −0.43) Urinary Leakage—S (1 month follow up, −0.32), Bowel Cramps—S (1 month follow up, −0.41; 7 month follow up, −0.39) O O O Erectile Dysfunction—S (1 month follow up, −0.57; 7 month follow up, −0.47) O O O S (7 month follow up, 0.17) Vitality—S (1 month follow up, −0.28; 7 month follow up, −0.26),
Kvam et al. (14) Multiple myeloma Then-test S (0.11) S (−0.07) O O O O O S (0.25) S (0.16) O O
Oort et al. (36) Lung; pancreas; esophageal; cervical Pre-test, post-test S (0.14) NS S (0.27) NS O O S (−0.11) O S (0.30) S Vitality—S (0.00)
Ousmen et al. (37) Breast Then-test Anchor-base 3 months—S (0.20), 6 months–NS 3 months–NS, 6 months—S (−0.32) 3 months—S (0.32), 6 months—S (0–0.29) 3 months—S (−0.29), 6 months—NS 3 months—S (−0.19), 6 months—S (−0.15) 3 months—NS, 6 months—NS 3 months—S (0.28), 6 months—S (−0.23) 3 months—NS, 6 months—S (0.41) 3 months—NS, 6 months—S (0.23) O Nausea and vomiting—NS, Dyspnea—NS, Financial */difficulties–NS, Insomnia—S 3 months, 0.22 0, Appetite Loss—S (6 months, 0.19), Constipation—S (6 months, 0.16), Diarrhea—NS, Body image—S (0.37, −0.23), Sexual enjoyment—NS, Future perspectives: 3 months—S (−0.27), 6 months—NS, Systemic therapy side effects—NS, Breast
symptoms—NS, Arm symptoms: 3 months—NS, 6 months—S (0.21)
Rees et al. (38) Prostate Then-test and pre-test, post-test O O O O O O O O O O Urinary Function—S
Salmon et al. (39) Breast SEM modeling O O O O O O O Mental fatigue: S (0.27) Physical fatigue: S (0.41) O O Activity reduction: S (0.59) Motivation reduction: S (0.43)
Sharpe et al. (13) Multiple, but primarily lung and colorectal Pre-test, post-test S O O O O O O O O O O
Sharpley and Christie (13) Breast Then-test O O O O O O O O O S (anxiety, 0.25; depression 0.13) O
Sprangers et al. (17) Breas; lung; prostate; Hodgkin Then-test O O O O NS O O S (0.94) O O O
Tessier et al. (41) Breast Pre-test, post-test O NS NS NS NS O S O O O NS—Life satisfaction
Traa et al. (42) Colorectal Pre-test, post-test O S O O O O S O O S Environment—S
Verdam et al. (43) Breast; prostate; lung; other Pre-test, post-test O S O O O O NS –RS—NS S –RS—NS Listlessness—NS; Sickness—S; Treatment related illness—NS
Verdam et al. (44) Breast; colorectal; lung; other Pre-test, post-test S (−0.19) NS NS NS O O S (-0.05) O NS S (0.08) Vitality—S (−0.34), Health Comparison—S
Visser et al. (45) Head and neck; gastrointestinal; gynecological; lung; breast; genitourinary tract; hematological malignancies; other Then-test O O O O O O O S O O O
Visser et al. (46) Lung; periampullary; esophageal; cervical Then-test, anchor recalibration S (−0.15) S (−0.58) S (−0.53) S (0.27) O O NS S (0.34) S (−0.49) S (0.39) Vitality—S (−0.31)
Visser et al. (4) Lung; periampullary; esophageal; cervical Then-test O O O O O O O O S O O
von Blackenburg et al. (47) Breast; lung; urologic; digestive system; gynecologic; other Pre-, post-test NS NS O O O O O O O S S—life goals
Westerman et al. (48) Lung Pre-test, post-test O O O O O O O S O O O

Effect sizes in parentheses when provided by authors; direction of the response shift effect is indicated by a negative (underestimation) or a positive (overestimation) sign.

MH, mental health; NS, not a statistically significant contributor; O, not assessed/considered in the model; QoL, quality of life; RS, response shift; S, statistically significant contributor; Sig, significant; Tx, treatment.