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. 2019 Aug 20;10:1978. doi: 10.3389/fimmu.2019.01978

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Copyright © 2019 Pinheiro, Mendes, Neves, Prado, Bittencourt-Mernak, Santana, Lago, de Sá, da Rocha, de Sousa, Fontes, Grisoto, Falcai and Lima-Neto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Efficacy of galloyl-HHDP-glucose treatments in reducing respiratory system and lung tissue elastance in lipopolysaccharide (LPS)-induced ALI mice. The respiratory system resistance (Rrs) and elastance (Ers), tissue damping (Gtis) and elastance (Htis), and airway resistance (Raw) (A–E). The mice received different doses of galloyl-HHDP-glucose (5, 50, and 100 mg/kg) 6 h after intra-tracheal instillation of LPS. The values are presented as mean and SD. Significances were calculated by One-way ANOVA followed by Tukey test. Significances were calculated by One-way ANOVA followed by Tukey test analysis of the groups vs. saline-injected non-treated mice (^*p < 0.05) and vs. lipopolysaccharide (LPS)-installed non-treated mice (^#p < 0.05).