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. 2019 Aug 20;10:855. doi: 10.3389/fneur.2019.00855

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Copyright © 2019 Scherg, Berg, Nakasato and Beniczky.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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What is our hypothesis? Three hypotheses are illustrated as mental starting points to understand the origin of the N100 peak of the LAEP. (A) Uni-focal: a single dipole (SD) or beamformer will localize to an equivalent center in the middle of the brain. (B) Smooth distribution: activity appears widely distributed in the Brain (LORETA); separate foci can be better isolated by iteration of the smeared images (CLARA). (C) Multifocal: what do the different brain regions contribute? Multiple discrete sources (RS1–RS3) model the three regions (AC L, AC R, CG) involved in the generation of this LAEP. The answer is the source waveforms shown on top.