Table 2.

Summary of regression analyses for the connectivity between left prefrontal regions and anterior default mode network.

Variable	B	p	95% Confidence interval
CONNECTIVITY BETWEEN LEFT BA6 AND ANTERIOR DMN
Overall model		0.44
APOE4	−0.093	0.75	−0.681	0.495
Amyloid	−0.030	0.87	−0.396	0.337
Sex	−0.091	0.15	−0.216	0.033
APOE4*amyloid	−0.008	0.98	−0.728	0.710
APOE4*sex	0.036	0.84	−0.306	0.379
Amyloid*sex	0.047	0.68	−0.180	0.273
APOE4*amyloid*sex	−0.019	0.93	−0.447	0.408
Age	0.005	0.10	−0.0009	0.011
Education	−0.001	0.90	−0.019	0.016
CONNECTIVITY BETWEEN LEFT BA44 AND ANTERIOR DMN
Overall model		0.05
APOE4	−0.378	0.20	−0.964	0.208
Amyloid	−0.265	0.15	−0.630	0.010
Sex	−0.100	0.11	−0.224	0.024
APOE4*amyloid	0.260	0.47	−0.456	0.976
APOE4*sex	0.156	0.37	−0.185	0.497
Amyloid*sex	0.178	0.12	−0.047	0.404
APOE4*amyloid*sex	−0.163	0.45	−0.589	0.263
Age	0.005	0.09	−0.0009	0.011
Education	0.007	0.44	−0.010	0.024
CONNECTIVITY BETWEEN LEFT BA8 AND ANTERIOR DMN
Overall model		0.23
APOE4	0.169	0.50	−0.330	0.669
Amyloid	0.252	0.11	−0.059	0.563
Sex	−0.038	0.48	−0.144	0.067
APOE4*amyloid	−0.507	0.10	−1.118	0.104
APOE4*sex	−0.126	0.39	−0.417	0.165
Amyloid*sex	−0.160	0.10	−0.352	0.032
APOE4*amyloid*sex	0.287	0.12	−0.076	0.650
Age	0.000	0.99	−0.005	0.005
Education	−0.003	0.69	−0.018	0.012
CONNECTIVITY BETWEEN LEFT BA9 AND ANTERIOR DMN
Overall model		0.19
APOE4	0.055	0.83	−0.450	0.559
Amyloid	0.351	0.03	0.037	0.666
Sex	−0.018	0.74	−0.125	0.089
APOE4*amyloid	−0.572	0.07	−1.188	0.045
APOE4*sex	−0.081	0.59	−0.374	0.213
Amyloid*sex	−0.224	0.02	−0.418	−0.030
APOE4*amyloid*sex	0.411	0.03	0.045	0.777
Age	−0.002	0.52	−0.007	0.004
Education	−0.001	0.89	−0.016	0.014

^*Connectivity in Fisher's z. APOE4, Apolipoprotein ε4 allele; BA, Brodmann area; DMN, Default Mode Network.