Table 3.

Summary of regression analyses for connectivity between left prefrontal regions and the posterior default mode network.

Variable	B	p	95% Confidence interval
CONNECTIVITY BETWEEN LEFT BA6 AND POSTERIOR DMN
Overall model		0.93
APOE4	−0.232	0.36	−0.726	0.263
Amyloid	0.030	0.16	−0.279	0.338
Sex	0.007	0.90	−0.098	0.111
APOE4*amyloid	0.254	0.41	−0.350	0.858
APOE4*sex	0.115	0.43	−0.173	0.403
Amyloid*sex	0.022	0.82	−0.168	0.212
APOE4*amyloid*sex	−0.153	0.40	−0.513	0.206
Age	−0.001	0.59	−0.007	0.004
Education	0.003	0.67	−0.012	0.018
CONNECTIVITY BETWEEN LEFT BA44 AND POSTERIOR DMN
Overall model		0.76
APOE4	−0.343	0.15	−0.805	0.120
Amyloid	−0.050	0.73	−0.338	0.239
Sex	0.035	0.48	−0.063	0.133
APOE4*amyloid	0.464	0.11	−0.102	1.029
APOE4*sex	0.167	0.22	−0.102	0.436
Amyloid*sex	0.025	0.78	−0.153	0.203
APOE4*amyloid*sex	−0.265	0.12	−0.602	0.071
Age	−0.0007	0.78	−0.005	0.004
Education	0.006	0.39	−0.008	0.020
CONNECTIVITY BETWEEN LEFT BA8 AND POSTERIOR DMN
Overall model		0.20
APOE4	0.117	0.71	−0.499	0.734
Amyloid	0.181	0.35	−0.203	0.565
Sex	0.082	0.22	−0.048	0.212
APOE4*amyloid	−0.197	0.61	−0.951	0.557
APOE4*sex	−0.077	0.67	−0.435	0.282
Amyloid*sex	−0.169	0.16	−0.406	0.069
APOE4*amyloid*sex	0.168	0.46	−0.280	0.616
Age	−0.008	0.02	−0.014	−0.001
Education	−0.015	0.12	−0.033	0.004
CONNECTIVITY BETWEEN LEFT BA9 AND POSTERIOR DMN
Overall model		0.003
APOE4	0.338	0.30	−0.304	0.979
Amyloid	0.252	0.21	−0.148	0.652
Sex	0.154	0.03	0.019	0.290
APOE4*amyloid	−0.467	0.24	−1.251	0.317
APOE4*sex	−0.230	0.23	−0.603	0.143
Amyloid*sex	−0.229	0.07	−0.475	0.018
APOE4*amyloid*sex	0.405	0.09	−0.061	0.872
Age	−0.011	0.002	−0.018	−0.004
Education	−0.020	0.04	−0.039	0.001

^*Connectivity in Fisher's z. APOE4, Apolipoprotein ε4 allele; BA, Brodmann area; DMN, Default Mode Network.