TABLE 1.

The reported proteins within cardiomyocyte-derived exosomes.

Exosomal cargo	Expression	Biological function	References
Hsp20	Increased	Promote angiogenesis; Improve cardiac function	Zhang et al., 2012; Yu et al., 2019
Hsp60	Increased	Promote immune responses	Gupta and Knowlton, 2007
Hsp70	Increased	Improve cardiac function	Feng et al., 2014
TNF-α	Increased	Contribute to cardiac remodeling	Yu et al., 2012
IL-6	Increased	Contribute to cardiac fibroblasts	Datta et al., 2017
GLUT1	Increased	Regulate metabolism	Garcia et al., 2016
GLUT4	Increased	Regulate metabolism	Garcia et al., 2016