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. 2019 Aug 20;10:894. doi: 10.3389/fneur.2019.00894

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Copyright © 2019 Saleh, Macia and Muotri.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transposable elements in the human genome. A schematic of the general structure of different classes of mobile elements. On the right is the estimated percentage present within the human genome. ITR, inverted terminal repeat; LTR, long terminal repeat; UTR, untranslated region. HERV genes include gag, which encodes viral structural proteins, pol, which encodes viral enzymes, and env, which encodes for the viral envelope protein. Black arrows indicate sense and antisense promoter regions. Black and gray double helices represent DNA. AAAA, represents polyA tail. This figure has been adapted from several reviews (5, 6).