Fig. 5.
Chronic LMX treatment prevents CORT-induced changes in excitatory transmission in anterior BLA. (a) Representative depiction comparing anterior BLA to posterior BLA. (b) Comparison of mean membrane capacitance (Cm; ****, p < 0.0001) and time constant (tau; **, p < 0.01) of pyramidal neurons from anterior and posterior BLA slices (c) Spontaneous EPSC (sEPSC) frequency (left) and amplitude (right) recorded from pyramidal neurons in anterior BLA and representative traces from each group (bottom). (d) sEPSC frequency (left) and amplitude (right) from posterior BLA principal neurons and representative traces (bottom). F and p-values for two-way ANOVA shown above (c–d). P values shown for pairwise comparisons derived from Holm-Sidak multiple comparisons test after ANOVA or unpaired student's two-tailed t-test (b). For cumulative probability curves, p < 0.0001 by K–S test. Each point represents one cell. Data are presented as mean ± SEM.