geometric parameters |
|
|
|
|
spiral artery radius (µm) |
— |
200 |
[5] |
|
trophoblast diameter (µm) |
30–40 |
40 |
[15,23] |
L |
length of decidual spiral artery modelled (mm) |
— |
1 |
see text |
Zp2 − Zp1
|
plug length (mm) |
>0.115 |
0.5 |
[23,24] |
Zp1
|
plug distance from IVS (mm) |
— |
0.1 |
— |
blood flow parameters |
|
|
|
μ |
blood viscosity (Pa s) |
0.003 |
0.003 |
[10,43] |
ΔP
|
pressure drop along segment of spiral artery (mmHg) |
— |
55 |
from [10] |
drag force |
|
|
|
|
kd
|
drag constant (N s m−1) |
— |
1.13 × 10−6
|
see text |
random force, Frandom
|
|
|
|
D |
diffusion constant (N) |
— |
2.83 × 10−13
|
fit to data |
flow force, Fflow
|
|
|
|
|
a |
constant of proportionality (N s m−1) |
— |
1.13 × 10−8
|
fit to data |
cell–wall interaction, Fcw
|
|
|
|
|
acw
|
scaling factor of the basic Fcw force function (N) |
— |
1.88 × 10−14
|
see text |
bcw
|
maximum attractive Fcw force (N) |
— |
1.04 × 10−14
|
fit to data |
r0
|
location of lower asymptote of force (fraction of cell diameter) |
— |
0.3 |
see text |
r1
|
location of upper asymptote of force (fraction of cell diameter) |
— |
1.7 |
see text |
cell–cell interaction, Fcc
|
|
|
|
acc
|
scaling factor of the basic Fcc force function (N) |
— |
1.88 × 10−14
|
see text |
bcc
|
maximum attractive Fcc force (N) |
— |
7.54 × 10−16
|
unknown |
r0
|
location of lower asymptote of force (fraction of cell diameter) |
— |
0.3 |
see text |
r1
|
location of upper asymptote of force (fraction of cell diameter) |
— |
1.7 |
see text |
chemotaxis, Fchem
|
|
|
|
|
fax
|
magnitude of chemoattractant force in axial direction (N) |
— |
1.88 × 10−16
|
unknown |
cax
|
coefficient controlling the penetration depth of axial chemoattractant force into the SA lumen (no units) |
— |
1 |
unknown |
frad
|
magnitude of chemoattractant force in radial direction (N m−1) |
— |
1.88 × 10−11
|
unknown |
crad
|
coefficient controlling the penetration depth of radial chemoattractant force into the SA lumen (no units) |
— |
1 |
unknown |