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. 2019 Aug 16;9(5):20190019. doi: 10.1098/rsfs.2019.0019

Table 1.

Model parameters, ranges and descriptions.

parameter description range value references
geometric parameters
rs spiral artery radius (µm) 200 [5]
Dp trophoblast diameter (µm) 30–40 40 [15,23]
L length of decidual spiral artery modelled (mm) 1 see text
Zp2Zp1 plug length (mm) >0.115 0.5 [23,24]
Zp1 plug distance from IVS (mm) 0.1
blood flow parameters
μ blood viscosity (Pa s) 0.003 0.003 [10,43]
ΔP pressure drop along segment of spiral artery (mmHg) 55 from [10]
drag force
kd drag constant (N s m−1) 1.13 × 10−6 see text
random force, Frandom
D diffusion constant (N) 2.83 × 10−13 fit to data
flow force, Fflow
a constant of proportionality (N s m−1) 1.13 × 10−8 fit to data
cell–wall interaction, Fcw
acw scaling factor of the basic Fcw force function (N) 1.88 × 10−14 see text
bcw maximum attractive Fcw force (N) 1.04 × 10−14 fit to data
r0 location of lower asymptote of force (fraction of cell diameter) 0.3 see text
r1 location of upper asymptote of force (fraction of cell diameter) 1.7 see text
cell–cell interaction, Fcc
acc scaling factor of the basic Fcc force function (N) 1.88 × 10−14 see text
bcc maximum attractive Fcc force (N) 7.54 × 10−16 unknown
r0 location of lower asymptote of force (fraction of cell diameter) 0.3 see text
r1 location of upper asymptote of force (fraction of cell diameter) 1.7 see text
chemotaxis, Fchem
fax magnitude of chemoattractant force in axial direction (N) 1.88 × 10−16 unknown
cax coefficient controlling the penetration depth of axial chemoattractant force into the SA lumen (no units) 1 unknown
frad magnitude of chemoattractant force in radial direction (N m−1) 1.88 × 10−11 unknown
crad coefficient controlling the penetration depth of radial chemoattractant force into the SA lumen (no units) 1 unknown