Table 1.
The lncRNA considered for our experiment.
| Gene | Function |
|---|---|
| BCAR4 a | Oncogenic, promotes invasion and metastasis15 |
| BCYRN1 | Oncogenic, promotes tumor progression16 |
| GAS5 a | Tumor suppressor17 |
| H19 a | Oncogenic, promotes proliferation and metastasis18 |
| HOTAIR a | Oncogenic, promotes EMT, proliferation, and metastasis19 |
| MALAT1 a | Oncogenic, promotes proliferation, invasion, and migration20 |
| MEG3 a | Tumor suppressor, induces accumulation of p5321 |
| PVT1 a | Oncogenic, promotes tumor progression22 |
| SOX2OT | Oncogenic, promotes tumor growth and metastasis23 |
| SRA1 a | Oncogenic24 |
| UCA1 a | Oncogenic, promotes cell growth, suppresses the tumor suppressor p2725 |
| XIST | Tumor suppressor26 |
Abbreviation: EMT, epithelial-mesenchymal transition.
a
The copy number variation available (among those lncRNAs, SRA1 transcribes both long noncoding and protein-coding RNAs which are produced by alternative splicing).