Table 1.
Studies in healthy adult populations that produced equations for reference values of six-minute walking distance.
| Study | Reference equations | Age range (years) | Number of patients | R 2 |
|---|---|---|---|---|
| Enright and colleagues21 | M: 7.57 × Height(cm)–5.02 × Age–1.76 × Weight(kg)– 309 F: 2.11 × Height(cm)– 2.29 × Weight(kg)–5.78 × Age + 667 |
>40 | 290 | M: 0.42 F: 0.38 |
| Troosters and colleagues22 | 218 + [5.14×Height(cm)–5.32 × Age]–1.8 × Weight(kg) + 51.31 × Sex, Sex: F = 0, M = 1 | 50–85 | 53 | 0.66 |
| Gibbons and colleagues23 | 794.1–2.99 × Age + 74.7 × Sex, Sex: F = 0, M = 1 | 20–80 | 79 | 0.41 |
| Enright and colleagues24 | M: 539 + 6.1 × Height(cm)–0.46 × Weight(kg)–5.8 × Age F: 493 + 2.2 × Height(cm)–0.93 × Weight(kg)–5.3 × Age |
⩾68 | 752 | M: 0.20 F: 0.20 |
| Chetta and colleagues25 | 479.78 + 1.25 × Height(cm)–2.82 × Age + 39.07 × Sex, Sex: F = 0, M = 1 | 20–50 | 102 | 0.42 |
| Camarri and colleagues26 | 182.86 + 4.12 × Height(cm)–1.75 × Age–1.15 × Weight(kg) + 34.04 × Gender, Sex: F = 0, M = 1 | 55–75 | 70 | 0.36 |
| Poh and colleagues27 | 5.50 × (HRmax/HRmax Predicted) + 6.94 × Height(cm)–4.49 × Age–3.51 × Weight(kg)–473.27 | 45–85 | 35 | 0.78 |
| Masmoudi and colleagues28 | 299.8–4.34 × Age + 3.43 × Height(cm)–1.46 × Weight(kg) + 62.5 × Sex, Sex: F = 0, M = 1 | 40–80 | 155 | 0.60 |
| Alameri and colleagues29 | 2.81 × Height(cm) + 0.79 × Age–28.5 | 16–50 | 298 | 0.25 |
| Ben Saad and colleagues30 | 560.50–5.14 × Age–2.23 × Weight(kg) + 2.72 × Height(cm) + 160 × Sex, Sex: F = 0, M = 1 | ⩾40 | 229 | 0.77 |
| Iwama and colleagues31 | 622.46–1.85 × Age + 61.50 × Sex, Sex: F = 0, M = 1 | 13–84 | 134 | 0.30 |
| Casanova and colleagues32 | 361– 4 × Age + 2× Height(cm)–1.5 × Weight(kg) + 3 × (HRmax/HRmax predicted)–30(if Female) | 40–80 | 440 | 0.38 |
| Dourado and colleagues33 | 299.30–2.73 × Age–2.16 × Weight(kg) + 361.73 × Height + 56.39 × Sex, Sex: F = 0, M = 1 | ⩾40 | 90 | 0.55 |
| Soaresa and colleagues34 | 511 + [0.0066 × Height(cm)2]–0.068 × (Age2 × 0.03–BMI2) | 20–80 | 132 | 0.55 |
| Britto and colleagues35 | 890.46–6.11 × Age + 0.035 × Age2 + 48.87 × Sex −4.87 × BMI, Sex: F = 0, M = 1 | ⩾18 | 617 | 0.46 |
| Duncan and colleagues36 | M: 290.6 × [Height (cm) × 0.525] × [Weight(kg)–0.317] × e–0.009 × Age
F: 260.3 × [Height (cm) × 0.525] × [Weight(kg)–0.317] × e–0.009 × Age |
50–85 | 246 | 0.53 |
| Oliveira and colleagues37 | 787.2–2.0 × Age–4.4 × BMI + 58.4 × Sex, Sex: F = 0, M = 1 | 18–70 | 158 | 0.38 |
BMI, body mass index; F, female; HR, heart rate; M, male; R2, a measure of the variance explained by the model/equation.