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. 2019 Aug 14;2019:5204218. doi: 10.1155/2019/5204218

Figure 1.

Figure 1

Effect of CSE and the thiol scavenger bacitracin on different pulmonary cell types. Effect of CSE exposure on (a) cell metabolic activity as determined by the MTT assay, n = 5‐11; (b) cell surface thiols, n = 4‐6; (c) release of CD63+CD81+ EVs determined by bead-based flow cytometry, n = 6‐13; (d) effect of 2.5 mM bacitracin on the release of CD63+CD81+ EVs, n = 5‐9. The box and whisker plots show the median (line in the box), 25th and 75th percentiles (outer lines of the box), and minimal and maximal values (whiskers). ∗ p < 0.05 compared to the untreated control (100%), # p < 0.05 for bacitracin compared to the vehicle control. Cell lines: BEAS-2B: bronchial epithelial cells; HEL-299 and MRC-5: pulmonary fibroblast cell lines; THP-1: monocyte-derived macrophages; HPMEC: human pulmonary microvascular endothelial cell line.