Table 1.
Univariate and multivariate Cox regression analyses estimating the risk factors of OS in ESCC patients.
| Variable | Univariate analyses | Multivariate analyses | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95% CI | p value | |
| Gender | 0.389 | 0.094-1.612 | 0.193 | |||
| Age | 0.683 | 0.268-1.738 | 0.424 | |||
| KPS | 1.237 | 0.674-2.271 | 0.493 | |||
| Drinking | 0.943 | 0.505-1.760 | 0.854 | |||
| Smoking | 1.449 | 0.762-2.756 | 0.258 | |||
| Weight loss | 1.116 | 0.579-2.152 | 0.742 | |||
| Histological grade | 0.832 | 0.454-1.527 | 0.553 | |||
| Location | 2.706 | 0.652-11.237 | 0.171 | |||
| Length | 1.991 | 0.949-4.177 | 0.069 | |||
| T stage | 2.718 | 1.250-5.913 | 0.012 | 3.168 | 0.320-31.376 | 0.324 |
| N stage | 3.464 | 1.841-6.517 | 0.000 | 5.194 | 0.547-49.265 | 0.151 |
| TNM stage | 2.218 | 1.428-3.171 | 0.000 | 0.537 | 0.064-4.508 | 0.567 |
| Resection margin | 0.935 | 0.226-3.875 | 0.926 | |||
| Adjuvant radiotherapy | 2.107 | 1.116-3.978 | 0.022 | 2.104 | 1.109-3.993 | 0.023 |
| Adjuvant chemotherapy | 1.829 | 0.941-3.556 | 0.075 | |||
| T-CTLA-4(-) +PLR (-) | 2.031 | 1.083-3.807 | 0.027 | 2.025 | 1.071-3.826 | 0.030 |
Abbreviations: OS: overall survival; ESCC: esophageal squamous cell carcinoma; HR: hazard ratio; CI: confidence interval; KPS: Karnofsky; T-CTLA-4: tumor cell cytotoxic T-lymphocyte-associated antigen-4; PLR: platelet lymphocyte ratio.