Table 2.
Clinicopathological characteristics of ESCC patients.
| Clinicopathological characteristics | N | T-CTLA-4(-) +PLR (-) | Other | p value |
|---|---|---|---|---|
| Gender | ||||
| Male | 66 | 30 | 36 | |
| Female | 6 | 2 | 4 | 0.686 |
| Age (years) | ||||
| <70 | 62 | 27 | 35 | |
| ≥70 | 10 | 5 | 5 | 0.703 |
| KPS | ||||
| >80% | 39 | 17 | 22 | |
| ≤80% | 33 | 15 | 18 | 0.874 |
| Weight loss (kg) | ||||
| <5 | 50 | 22 | 28 | |
| ≥5 | 22 | 10 | 12 | 0.909 |
| Drinking | ||||
| Yes | 32 | 13 | 19 | |
| No | 40 | 19 | 21 | 0.560 |
| Smoking | ||||
| Yes | 46 | 21 | 25 | |
| No | 26 | 11 | 15 | 0.784 |
| Histological differentiation | ||||
| Well and moderate | 39 | 15 | 24 | |
| Poor | 33 | 17 | 16 | 0.267 |
| Location | ||||
| Proximal third | 7 | 3 | 4 | |
| Middle third | 43 | 17 | 26 | |
| Distal third | 22 | 12 | 10 | 0.513 |
| Tumor length (cm) | ||||
| <3 | 18 | 10 | 8 | |
| ≥3 | 54 | 22 | 32 | 0.273 |
| Infiltration depth | ||||
| T1 and T2 | 21 | 11 | 10 | |
| T3 and T4 | 51 | 21 | 30 | 0.384 |
| Lymph node status | ||||
| N0 | 47 | 23 | 24 | |
| N1 | 25 | 9 | 16 | 0.293 |
| pTNM staging | ||||
| I and II | 48 | 23 | 25 | |
| III | 24 | 9 | 15 | 0.402 |
| Resection margin | ||||
| Positive | 3 | 1 | 2 | |
| Negative | 69 | 31 | 38 | 1.000 |
| Adjuvant radiotherapy | ||||
| Yes | 19 | 7 | 12 | |
| No | 53 | 25 | 28 | 0.437 |
| Adjuvant chemotherapy | ||||
| Yes | 16 | 5 | 11 | |
| No | 56 | 27 | 29 | 0.228 |
Abbreviations: T-CTLA-4: tumor cell cytotoxic T-lymphocyte-associated antigen-4; PLR: platelet lymphocyte ratio; ESCC: esophageal squamous cell carcinoma; KPS: Karnofsky.