Table 3.

TBQ final questionnaire scores per item

TBQ Item	Score, mean (SD)
1. The taste, shape or size of your tablets and/or the annoyances by your injections	2.6 (3.2)
2. The numbers of times you should take your medication daily	1.8 (2.3)
3. The efforts you make not to forget to take your medications	2.5 (2.9)
4. The necessary precautions when taking your medication	2.1 (2.8)
5. Lab Tests and other exams: frequency, time spent and associated nuisances or inconveniences	2.8 (2.6)
6. Self-monitoring: frequency, time spent and inconveniences	0.5 (1.3)
7. Doctor visits and other appointments: frequency, time spent for these visits and difficulties findings healthcare providers	2.7 (2.8)
8. Difficulties in relationships with healthcare providers	1.6 (2.6)
9. Arranging medical appointments and/or transportation and reorganizing schedules around these appointments	3.3 (3.1)
10. Administrative burden related to healthcare	4.2 (3.4)
11. Financial burden associated with healthcare	3.2 (3.2)
12. Burden related to dietary changes	2.1 (2.8)
13. Burden related to doctors recommendations to practice physical activity	3.0 (3.2)
14. Impact of healthcare on relationships with others	3.0 (3.4)
15. Anxiety generated by uncertainty over results of medical checkups and complementary studies to know if treatment is working	3.6 (3.5)
16. The need for medical healthcare on a regular basis reminds me of my health problem	2.9 (3.2)