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. 2019 Jul 16;46:54–65. doi: 10.1016/j.ebiom.2019.07.030

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© 2019 Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — CDCA5 promotes ESCC cells proliferation, migration and invasion. (a) CDCA5 knockdown induced apoptosis in both KYSE30 and Eca109 cells according to the flow cytometric analysis (Mean ± SD, Student's t-test, ***P < .001); (b) CDCA5 knockdown inhibited ESCC cells invasion in KYSE30 and Eca109 cells, (Mean ± SD, Student's t-test, ***P < .001); (c) Knockdown of CDCA5 inhibited the migration of tumor cells in KYSE30 and Eca109 cells, (Mean ± SD, Student's t-test, ***P < .001); (d) The efficiency of CDCA5 overexpression in KYSE150 (Mean ± SD, Student's t-test, ***P < .001); (e) Overexpression of CDCA5 promoted the proliferation of KYSE150 cells (Mean ± SD, Student's t-test, ***P < .001); (f) CDCA5 overexpression promoted KYSE150 cells invasion and migration (Mean ± SD, Student's t-test, ***P < .001).