TABLE 1.
IC and MFC of tempol against C. albicans | |||
Tempol | ATP | OD530 (nm) | Agar-spot assay |
Tested concentration | 0.05–17 | 0.05–17 | – |
range (mg/ml) | |||
IC90a | 0.68 | 0.5 | – |
IC50b | 0.15 | 0.3 | – |
MFCc | – | – | 0.5 |
a,bInhibitory concentration (IC) was determined as the lowest concentration of tempol that inhibited fungal growth at ≥90% aIC90 or ≥50% bIC50; Data from three independent experiments. cMinimum fungicidal concentration (MFC) was determined as the lowest concentration of tempol that killed at least 99.9% of the initial inoculum. Data from three independent experiments.