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. 2019 Aug 20;10:1843. doi: 10.3389/fmicb.2019.01843

TABLE 1.

In vitro activity of tempol against C. albicans SC5314 assessed by 3 different methods.

IC and MFC of tempol against C. albicans
Tempol ATP OD530 (nm) Agar-spot assay
Tested concentration 0.05–17 0.05–17
range (mg/ml)
IC90a 0.68 0.5
IC50b 0.15 0.3
MFCc 0.5

a,bInhibitory concentration (IC) was determined as the lowest concentration of tempol that inhibited fungal growth at ≥90% aIC90 or ≥50% bIC50; Data from three independent experiments. cMinimum fungicidal concentration (MFC) was determined as the lowest concentration of tempol that killed at least 99.9% of the initial inoculum. Data from three independent experiments.