Table 2.
Change in TICS‐M Score by Intensity of Statin Therapy
| Statin Regimen at Dischargea | P Value | |||||
|---|---|---|---|---|---|---|
| Other, n = 1 | None, n = 54 | Low, n = 62 | Moderate, n = 87 | High/Goal, n = 112 | ||
| Change in TICS‐M from 1 to 6 months, mean ± SD | 3.0 | −0.4 ± 5.5 | −0.4 ± 7.0 | 0.7 ± 5.2 | −0.1 ± 5.2 | 0.70 |
| Relative change in TICS‐M from 1 to 6 months, n (%) | ||||||
| ≥15% increase | 1 (100) | 38 (70) | 47 (76) | 74 (85) | 95 (85) | 0.12 |
| <15% decrease | 0 (0) | 16 (30) | 15 (24) | 13 (15) | 17 (15) | |
Abbreviations: ANOVA, analysis of variance; SD, standard deviation; TICS‐M, Modified Telephone Interview for Cognitive Status.
Comparisons made using 1‐way ANOVA.
a
Low‐intensity statin defined as simvastatin 10 mg, pravastatin 10 mg–20 mg, lovastatin 20 mg, fluvastatin 20 mg–40 mg; moderate therapy as atorvastatin 10 mg–20 mg, rosuvastatin 10 mg, simvastatin 20 mg–40 mg, pravastatin 40 mg–80 mg, lovastatin 40 mg; high/goal therapy as atorvastatin 80 mg, rosuvastatin 20 mg–40 mg.